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Assisted reproduction

Low Complexity

  • This procedure is done through the use of drugs with the objective of maturing an oocyte and therefore increase the possibility of pregnancy ; also can be controlled quite reliable, the time of ovulation.

    It starts from the second or third day of menstruation and is monitored through ultrasound ; once the follicle has reached an adequate size (18 to 20mm), ovulation is induced through medication and approximate time of ovulation is determined.

It is a simple, quick , painless procedure and is performed in office. It is to introduce into the uterine cavity of women through a thin catheter , the selected sperm sample and previously trained in the laboratory. o make an IIU is needed to monitor ovulation by ultrasound during a natural cycle or stimulated cycle .

The IIU it can be of two types :

Insemination intrauterine homologous: 

That is with the sperm of the couple. Is performed when sperm count is below normal limits , when infertility is immunologically mediated , in cases diagnosed endometriosis or when unexplained.

Insemination intrauterine heterologous: 

That is with donor sperm . It is performed when the partner’s sperm or no sperm has low sperm quality . In these cases , the sample will be selected from our Sperm Bank.

High Complexity


These treatments are indicated in the following cases:

  • When the fallopian tubes are blocked
  • When impaired semen quality exists
  • When there are immunological disorders
  • When the cause of infertility is unknown, despite having made all diagnostic tests available and made four ( 04) Intrauterine inseminations.
  • In patients diagnosed with endometriosis .
  • In other cases determined by the doctor.
Also known as test-tube baby , it is to join in the laboratory oocytes obtained by follicular aspiration and sperm previously trained in the laboratory. Once fertilized oocytes and formed embryos are transferred to the woman’s uterus to continue development naturally.

It is a method comprising the following steps:

Hyperstimulation controlled ovarian: 

It is done through a hormonal treatment to ensure multiple follicular development. This process starts between the second and third day of menstruation , lasts approximately 10 days and goes through monitoring or transvaginal ultrasound(ultrasound monitoring ovulation).

Follicular aspiration: 

It is carried out in a coordinated manner by the professional team whose main goal is to retrieve the eggs contained within follicles . It is performed under epidural or intravenous anesthesia, and intravaginal ultrasound-guided. This procedure takes about 40 minutes and then the patient rests an average of 2 hours to later return home.

Oocyte insemination: 

It is performed in the laboratory after evaluating the quality of oocytes and sperm sample train by placing a droplet of sperm trained for each egg. fertilization and every 24 hours then evaluates cell multiplication.

Embryo transfer (TE): 

It is the procedure that is deposited in the woman’s uterus embryos generated in the laboratory of IVF between day 3 and 5 of life of the embryo . This procedure is performed without anesthesia on an outpatient basis .

This technique involves the microinjection of a sperm into an oocyte or ovum previously prepared.

It is done when you can not perform conventional IVF because:

  • Severe male factor
  • Fertilization failure in FIV
  • Azoospermia
  • etc.

The steps for ICSI are the same as for FIV.

It is to perform the procedure ICSI with donor eggs and sperm of the couple. Once formed embryos will be transferred to the recipient’s uterus to continue the pregnancy.

This technique is reserved for patients who have problems in their ovaries ( early menopause , elderly , etc. ) or suffer from any genetic disease transmissible from parent to child.

Donors are women between 18 and 30 years who have undergone a full assessment to meet their physical, mental , family history, race, size , texture , color of skin, eyes and hair to select those that have physical resemblance to the recipient.

IVM for its acronym in English..

It is a technique that involves obtaining oocytes in a developmental stage earlier than with conventional techniques of assisted reproduction. Because of this, these oocytes still require a final maturation process in vitro , using suitable culture media and conditions that preserve their quality and capacity development.

As assisted reproduction technique , in vitro maturation has undergone substantial improvements in the last decade , which has resulted in an increase in the odds of pregnancy. CEFRA is one of the few centers in the world offering this technique.

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Advantages of in vitro Maturation:

  • The most common complication in women following fertility treatment is ovarian hyperstimulation syndrome . This complication has not been reported in patients treated by the technique of in vitro maturation of oocytes.
  • It has further been reported that prior to hormonal treatment in vitro maturation causes less discomfort in the patient during follicular aspiration.
  • By using a milder and shorter ovarian stimulation , costs are lowered .

Disadvantages Maturation in vitro :

  • Success rates are slightly lower than with other assisted reproduction techniques


It is a technique that allows us to keep sperm at low temperatures (-196ºC) and keep them for long periods without losing their fertilising capacity.

Cryopreservation is indicated in patients who are to undergo vasectomy, chemotherapy or radiation treatments , as well as those who for various reasons have difficulty obtaining a normal ejaculation (erectile dysfunction , retrograde ejaculation) or very poor sperm quality ; or in those patients because of travel or residence outside the country will not be present during the conduct of fertility procedure .

Sperm Bank

  • Patients: We offer the freezing and storage of semen sample to patients in need (for travel, cancer treatment , etc.)
  • Donors: It has frozen semen samples from male donors who have been previously evaluated from psychological , physical and discarding aspects infections .

All frozen samples have a period of 6 months observation before being used .

Oocyte Vitrification is a technique that offers excellent possibilities for preserving the fertility of women. Every woman of childbearing age can freeze their eggs when she decides and use them for breeding years later.

This technique is indicated in women with:

  • Risk of losing their reproductive capacity by oncological diseases (cancer),
  • Background of endometriosis,
  • Family history of premature menopause,
  • Professional development before age 35,
  • etc.

During in vitro culture , embryos can be frozen for later transfer in a (natural or artificial) cycle deferred . Vitrification is usually performed on days 3 or 5 embryo culture .


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  • Vitrification of embryos on Day 3 consists of freezing embryos on day 3 of life , in the State of cleavage .
  • Vitrification of Day 5 is the freezing of embryos on day 5 of embryonic life and allows “self ” In Vitro, being finally obtained blastocysts those with better prognosis.

In this way , the patient will have the option to thaw and transfer embryos at any time , prior coordination and preparation by specialists .